Author: Bankless; Compiler: Felix, PANews

On the eve of the BIO Protocol token issuance, DeSci (decentralized (chemical science) ecology’s token prices have been soaring.

As the boundaries between cutting-edge technologies such as DeSci and AI gradually blurred, this craze continued until the launch of BIO and was reflected in the focus on the technologies related to these technologies. on the token. As a key hub for DeSci's financing, the launch of BIO has brought hope to DeSci, spawned outside enthusiasm for this highly experimental field, and attracted more attention and capital to DeSci over time.

This article will provide an in-depth look at how the BIO Protocol works, the challenges it attempts to solve, and the DAOs that operate under its umbrella. Then explore how other projects fill the DeSci narrative and provide additional tools or use cases to transform how science is collaborated and funded.

BIO Protocol is essentially a decentralized token management platform that supports and incubates specialized BioDAO. By bringing funding decisions, intellectual property ownership, and governance on-chain, BIO directly addresses several long-standing obstacles in biotech:

Helping early-stage projects escape "Valley of Death", insufficient funds often hinder the implementation of promising ideas

Tokenize research results, promote open access and transparent cooperation, and resist data and The island of intellectual property

Replace opaque R&D with real-time on-chain fund flow and results tracking

To achieve these goals, BIO has implemented several core mechanisms:

To achieve these goals, BIO has implemented several core mechanisms:

Curation

BIO holders lock their tokens (vBIO) to Helps determine which new BioDAOs are allowed to join the network. This process ensures that only the most promising or community-supported businesses join, as those who pledge support must stake BIO for a certain period. If you getSubject to approval, stakers can exclusively participate in BioDAO’s financing round.

Funds and Liquidity

After completing the curation phase, BioDAO opens a private pre-seed auction for those who lock in vBIO.

This allows early backers of DAOs and the BIO community to invest in early-stage scientific research on terms traditionally reserved for VCs. At the same time, BIO Protocol manages liquidity on behalf of these BioDAOs, eliminating the need to oversee secondary markets. The BIO Vault pairs tokens (i.e. VITA/BIO or HAIR/BIO) with ETH or other assets, generating fees for the protocol while ensuring a stable trading pair. This arrangement allows BioDAO to focus on advancing research rather than busying itself with market operations.

Meta-Governance

Since the BIO Vault holds a portion of each BioDAO token, BIO holders collectively gain influence within the broader DeSci ecosystem.

This meta-governance structure enables them to guide multiple BioDAO decisions, whether setting research priorities or emphasizing synergies between projects. Additionally, by diversifying the Treasury’s holdings, the agreement enhances its ability to invest in new projects and reinvest in existing projects, allowing for seamless coordination across an expanding range of scientific research areas.

Provide benefits

To incentivize clear, measurable contributions to its network, BIO issues "bio/acc rewards" in the form of additional BIO tokens to BioDAOs that achieve key milestones. In addition to these incentives, BioDAO can tokenize its IP, from research data to patents. By issuing IP tokens, BioDAO can grant partial ownership of its research results, allowing more stakeholders to benefit from future scientific breakthroughs, while retaining control over key decisions and potentially generating revenue from the use of its data.

In addition to direct incentives, the overall value of the network grows through token allocations and the liquidity owned by the protocol. Grants to new BioDAOs are exchanged for a small stake in their tokens, while liquidity pool fees flow back to the treasury . As BioDAO matures and produces tangible results, the total value of these assets will increase, thereby strengthening the virtuous cycle of financing, growth and innovation.

Currently, there are eight in the BIO network BioDAO is active, each focusing on a specific research area

VitaDAO | $VITA

;">VitaDAO launches in 2021 to support research that extends human lifespan. Funded by Pfizer Ventures and Balaji Srinivasan, it explores the biological mechanisms of aging, including neurodegenerative diseases.

Quantum Biology DAO

Quantum Biology DAO studies how weak magnetic fields affect cells at the quantum level. It collaborates with the Institute of Quantum Biology to develop Quantum microscopy opens up new avenues for longevity research, drug discovery, etc.

HairDAO | HAIR

HairDAO Joining forces with patients, researchers and funders to solve the under-resourced problem of hair loss

ValleyDAO | $GROW

ValleyDAO is committed to pursuing synthetic biology solutions to combat climate change, such as engineering microorganisms to capture carbon dioxide or produce biodegradable materials.

AthenaDAO | $ATH

AthenaDAO focuses on women's health, filling a gap that traditional funding ignores. Through a decentralized community of patients, scientists, and advocates, it supports reproductive health, hormonal imbalances, and more. Projects on under-researched topics in female biology

CryoDAO | $CRYO

CryoDAO directs funds to cryopreservation research to improve organ and tissue storage, a technology with life-saving potential Scheme.

PsyDAO | $PSY

PsyDAO Focused on psychedelic research for mental health issues such as depression, addiction, and PTSD, it uses a decentralized funding model and AI-based auditing to accelerate the discovery of new compounds, while on-chain governance. Ensures transparency of resource allocation

CerebrumDAO | $NEURON

CerebrumDAO. Convening a global community to prevent neurodegeneration and prolong brain health. It studies diseases such as Alzheimer's, focusing on inflammation, metabolic issues, the blood-brain barrier and its impact

In addition to the BIO Protocol ecosystem, there are many interesting DeSci projects that bring new platforms or tools for scientific research discovery.

ResearchHub Foundation

The ResearchHub Foundation, founded by Coinbase CEO Brian Armstrong and Patrick Joyce, uses RSC to create a forum for publishing and reviewing science. Open platform. Contributors earn RSCs by publishing research, curating content, or contributing to discussions. The platform’s goal is to build a “GitHub” for scientific research, designed to simplify peer review, encourage open sharing, and bring real-time accountability to scholarly publishing. system, all achieved through token incentives. Holders can also vote on platform improvements and reward distribution

yesnoerror

Yesnoerror is a decentralized platform that combines AI with community-driven oversightCombined, it aims to improve the reliability of scientific research papers. Its AI engine continuously scans research for inaccuracies—whether in data, statistical analysis, or references—and flags potential issues for further review. Community members who verify or correct these errors will be awarded YNE tokens, creating an intrinsic incentive for thorough review and timely feedback.

Overall, YNE hopes to detect problems early to prevent incorrect conclusions, reduce the risk of poor decision-making and wasted research, and develop a system that can learn from users. AI to better detect problems across a range of different scientific fields.

pump.Science

Pump.science is a DeSci platform designed to identify and develop chemicals that can extend human health span. It hopes to gamify research by conducting low-cost tests on simple organisms (worms, flies) before using complex models (mice). This approach allows for the early identification of promising interventions, using cryptocurrency-based funding to propose or invest in new compounds. By live-streaming experiments, the protocol provides real-time data, allowing both researchers and speculators to track results and potentially adjust their support as research progresses.

BIO Protocol’s token issuance puts the DeSci field in the spotlight, demonstrating how a new generation of on-chain initiatives can reshape research and development in biotechnology and other fields.

Beyond the BIO ecosystem, other DeSci projects demonstrate complementary strategies for enhancing scientific research through blockchain. From ResearchHub’s open collaboration platform to yesnoerror’s AI-powered paper audits and pump.science’s gamified longevity experiments, these projects explore the intersection of science and crypto from different angles. Taken together, they point to a rapidly evolving DeSci landscape where shared governance, financial coordination, and real-time data sharing may lead to new breakthroughs.

Whether solving funding bottlenecks, streamlining peer review, or discovering life-extending molecules, DeSci's solutions have audacious goals and enable broad, proactive community to explore discoveries, ultimately accelerating the rate at which the world benefits from the next wave of scientific innovation.